Haloperidol

pronounced as (ha loe per' i dole)

Brand Name(s): Haldol®, also available generically

Why is this medicine prescribed?

Haloperidol is used to treat psychotic disorders (conditions that cause difficulty telling the difference between things or ideas that are real and things or ideas that are not real). Haloperidol is also used to control motor tics (uncontrollable need to repeat certain body movements) and verbal tics (uncontrollable need to repeat sounds or words) in adults and children who have Tourette's disorder (condition characterized by motor or verbal tics). Haloperidol is also used to treat severe behavioral problems such as explosive, aggressive behavior or hyperactivity in children who cannot be treated with psychotherapy or with other medications. Haloperidol is in a group of medications called conventional antipsychotics. It works by decreasing abnormal excitement in the brain.

Are there other uses for this medicine?

Haloperidol is also used to treat confusion and difficulty thinking and understanding that is caused by severe physical or mental illness. Talk to your doctor about the possible risks of using this medication for your condition.

This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.

How should this medicine be used?

Haloperidol comes as a tablet and concentrated liquid to take by mouth. It is usually taken two or three times a day. Take haloperidol at around the same times every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take haloperidol exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

Your doctor will probably start you on a low dose of haloperidol and gradually increase your dose. Your doctor may decrease your dose once your condition is controlled. Be sure to tell your doctor how you are feeling during your treatment with haloperidol.

Haloperidol may help control your condition, but will not cure it. Continue to take haloperidol even if you feel well. Do not stop taking haloperidol without talking to your doctor. Your doctor will probably decrease your dose gradually. If you suddenly stop taking haloperidol, you may experience difficulty controlling your movements.

What special precautions should I follow?

Before taking haloperidol,

  • tell your doctor and pharmacist if you are allergic to haloperidol or any other medications.
  • tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take while taking haloperidol. Your doctor may need to change the doses of your medications or monitor you carefully for side effects.
  • tell your doctor if you have or have ever had Parkinson's disease (PD; a disorder of the nervous system that causes difficulties with movement, muscle control, and balance). Your doctor will probably tell you not to take haloperidol.
  • tell your doctor if you or anyone in your family has or has ever had prolonged QT syndrome (condition that increases the risk of developing an irregular heartbeat that may cause loss of consciousness, or sudden death). Also tell your doctor if you have or have ever had breast cancer; bipolar disorder (condition that causes episodes of depression, episodes of mania, and other abnormal moods); citrullinemia (condition that causes build-up of ammonia in the blood); an abnormal electroencephalogram (EEG; a test that records electrical activity in the brain); seizures; an irregular heartbeat; low levels of calcium or magnesium in your blood; trouble keeping your balance; chest pain; or heart or thyroid disease. Also tell your doctor if you have ever had to stop taking a medication for mental illness due to severe side effects.
  • tell your doctor if you are pregnant, especially if you are in the last few months of your pregnancy, or if you plan to become pregnant or are breast-feeding. If you become pregnant while taking haloperidol, call your doctor. Haloperidol may cause problems in newborns following delivery if it is taken during the last months of pregnancy.
  • you should know that this medication may make you drowsy and may affect your thinking and movements. Do not drive a car or operate machinery until you know how this medication affects you.
  • you should know that haloperidol may cause dizziness, lightheadedness, and fainting when you get up too quickly from a lying position. To avoid this problem, get out of bed slowly, resting your feet on the floor for a few minutes before standing up.
  • if you are having surgery, including dental surgery, tell the doctor or dentist that you are taking haloperidol.
  • ask your doctor about the safe use of alcohol during your treatment with haloperidol. Alcohol can make the side effects of haloperidol worse.

What special dietary instructions should I follow?

Unless your doctor tells you otherwise, continue your normal diet.

What should I do if I forget to take a dose?

Take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.

What should I do in case of overdose?

In case of overdose, call the poison control helpline at 1-800-222-1222. Information is also available online at https://www.poisonhelp.org/help . If the victim has collapsed, had a seizure, has trouble breathing, or can't be awakened, immediately call emergency services at 911.

Symptoms of overdose may include:

  • unusual, slowed, or uncontrollable movements of any part of the body
  • stiff or weak muscles
  • slowed breathing
  • sleepiness
  • loss of consciousness

What side effects can this medicine cause?

Haloperidol may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

  • dry mouth
  • increased saliva
  • blurred vision
  • loss of appetite
  • constipation
  • diarrhea
  • heartburn
  • nausea
  • vomiting
  • difficulty falling asleep or staying asleep
  • blank facial expression
  • uncontrollable eye movements
  • unusual, slowed, or uncontrollable movements of any part of the body
  • restlessness
  • agitation
  • nervousness
  • mood changes
  • dizziness, feeling unsteady, or having trouble keeping your balance
  • headache
  • breast enlargement or pain
  • breast milk production
  • missed menstrual periods
  • decreased sexual ability in men
  • increased sexual desire
  • difficulty urinating

If you experience any of the following symptoms, call your doctor immediately:

  • fever
  • muscle stiffness
  • falling
  • confusion
  • fast or irregular heartbeat
  • sweating
  • decreased thirst
  • neck cramps
  • tongue that sticks out of the mouth
  • tightness in the throat
  • difficulty breathing or swallowing
  • fine, worm-like tongue movements
  • uncontrollable, rhythmic face, mouth, or jaw movements
  • seizures
  • eye pain or discoloration
  • decreased vision, especially at night
  • seeing everything with a brown tint
  • rash
  • yellowing of the skin or eyes
  • erection that lasts for hours

Haloperidol may cause other side effects. Tell your doctor if you have any unusual problems while you are taking this medication.

If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online ( http://www.fda.gov/Safety/MedWatch ) or by phone (1-800-332-1088).

What should I know about storage and disposal of this medication?

Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom). Protect the liquid from light and do not allow it to freeze.

Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. However, you should not flush this medication down the toilet. Instead, the best way to dispose of your medication is through a medicine take-back program. Talk to your pharmacist or contact your local garbage/recycling department to learn about take-back programs in your community. See the FDA's Safe Disposal of Medicines website ( http://goo.gl/c4Rm4p ) for more information if you do not have access to a take-back program.

It is important to keep all medication out of sight and reach of children as many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and young children can open them easily. To protect young children from poisoning, always lock safety caps and immediately place the medication in a safe location – one that is up and away and out of their sight and reach. http://www.upandaway.org

What other information should I know?

Keep all appointments with your doctor.

Do not let anyone else take your medication. Ask your pharmacist any questions you have about refilling your prescription.

It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.

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