Diethylpropion

pronounced as (dye eth il proe' pee on)

Brand Name(s): Tenuate®, Tenuate® Dospan, Tepanil®, also available generically

Why is this medicine prescribed?

Diethylpropion decreases appetite. It is used on a short-term basis (a few weeks), in combination with diet, to help you lose weight.

This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information.

How should this medicine be used?

Diethylpropion comes as a regular and extended-release (long-acting) tablet. Diethylpropion usually is taken three times a day, 1 hour before meals (regular tablets), or once a day in midmorning (extended-release tablets). Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take diethylpropion exactly as directed.

Do not crush, chew, or cut extended-release tablets; swallow them whole.

Diethylpropion may be habit-forming. Do not take a larger dose, take it more often, or for a longer period than your doctor tells you to. Call your doctor if diethylpropion loses its effect.

What special precautions should I follow?

Before taking diethylpropion,

  • tell your doctor and pharmacist if you are allergic to diethylpropion; amphetamines; other diet pills; medications for allergies, hay fever, and colds; or any other drugs.
  • tell your doctor or pharmacist if you are taking the following medications or have stopped taking them within the past two weeks: MAO inhibitors [phenelzine (Nardil) or tranylcypromine (Parnate)].
  • tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take while taking diethylpropion. Your doctor may need to change the doses of your medications or monitor you carefully for side effects.
  • tell your doctor if you have or have ever had heart or blood vessel disease, high blood pressure, an overactive thyroid gland, diabetes, glaucoma, pulmonary hypertension, seizures, or a history of drug abuse.
  • tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking diethylpropion, call your doctor.
  • you should know that this drug may make you drowsy. Do not drive a car or operate machinery until you know how this drug affects you.
  • if you are having surgery, including dental surgery, tell the doctor or dentist that you are taking diethylpropion.
  • remember that alcohol can add to the drowsiness caused by this drug.

What special dietary instructions should I follow?

Follow your doctor's directions. Eat a low-calorie, well-balanced diet.

What should I do if I forget to take a dose?

Take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.

What should I do in case of overdose?

In case of overdose, call the poison control helpline at 1-800-222-1222. Information is also available online at https://www.poisonhelp.org/help . If the victim has collapsed, had a seizure, has trouble breathing, or can't be awakened, immediately call emergency services at 911.

What side effects can this medicine cause?

Diethylpropion may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

  • dry mouth
  • unpleasant taste
  • restlessness
  • anxiety
  • dizziness
  • depression
  • tremors
  • upset stomach
  • vomiting
  • increased urination

If you experience any of the following symptoms, call your doctor immediately:

  • fast or irregular heartbeat
  • heart palpitations
  • blurred vision
  • skin rash
  • itching
  • difficulty breathing
  • chest pain
  • fainting
  • swelling of the ankles or feet
  • fever
  • sore throat
  • chills
  • painful urination

If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online ( http://www.fda.gov/Safety/MedWatch ) or by phone (1-800-332-1088).

What should I know about storage and disposal of this medication?

Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom).

Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. However, you should not flush this medication down the toilet. Instead, the best way to dispose of your medication is through a medicine take-back program. Talk to your pharmacist or contact your local garbage/recycling department to learn about take-back programs in your community. See the FDA's Safe Disposal of Medicines website ( http://goo.gl/c4Rm4p ) for more information if you do not have access to a take-back program.

It is important to keep all medication out of sight and reach of children as many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and young children can open them easily. To protect young children from poisoning, always lock safety caps and immediately place the medication in a safe location – one that is up and away and out of their sight and reach. http://www.upandaway.org

What other information should I know?

Keep all appointments with your doctor. Your doctor may order certain tests to check your response to diethylpropion.

Diethylpropion may affect blood sugar levels of diabetic patients and may cover up some signs and symptoms of hypoglycemia (low blood sugar). If you notice a change in the results of your urine or blood sugar tests, check with your doctor.

Do not let anyone else take your medication. Ask your pharmacist any questions you have about refilling your prescription.

It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.

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