Belatacept Injection

pronounced as (bel at' a sept)

Brand Name(s): Nulojix®

Why is this medicine prescribed?

Belatacept injection is used in combination with other medications to prevent rejection (attack of a transplanted organ by the immune system of a person receiving the organ) of kidney transplants. Belatacept injection is in a class of medications called immunosuppressants. It works by decreasing the activity of the immune system to prevent it from attacking the transplanted kidney.

Are there other uses for this medicine?

This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.

How should this medicine be used?

Belatacept injection comes as a solution (liquid) to be injected over 30 minutes into a vein, usually by a doctor or nurse in a hospital or medical facility. It is usually given on the day of transplant, 5 days after transplant, at the end of weeks 2 and 4, then once every 4 weeks.

Your doctor will monitor you carefully. Talk to your doctor about how you are feeling during your treatment.

What special precautions should I follow?

Before receiving belatacept injection,

  • tell your doctor and pharmacist if you are allergic to belatacept or any other medications, or any of the ingredients in belatacept injection. Ask your pharmacist or check the Medication Guide for a list of the ingredients.
  • tell your doctor and pharmacist what other prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Your doctor may need to change the doses of your medications or monitor you carefully for side effects.
  • tell your doctor if you have any medical conditions.
  • tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking belatacept injection, call your doctor.
  • plan to avoid unnecessary or prolonged exposure to sunlight, tanning beds, and sun lamps. Belatacept may make your skin sensitive to sunlight. Wear protective clothing, sunglasses, and sunscreen with a high protection factor (SPF) when you have to be in the sun during your treatment.
  • do not have any vaccinations without talking to your doctor.
  • if you are having surgery, including dental surgery, tell the doctor or dentist that you are receiving belatacept injection.

What special dietary instructions should I follow?

Unless your doctor tells you otherwise, continue your normal diet.

What should I do if I forget to take a dose?

If you miss an appointment to receive belatacept injection, call your doctor as soon as possible.

What should I do in case of overdose?

In case of overdose, call the poison control helpline at 1-800-222-1222. Information is also available online at . If the victim has collapsed, had a seizure, has trouble breathing, or can't be awakened, immediately call emergency services at 911.

Symptoms of overdose may include the following:

  • confusion
  • difficulty remembering
  • change in mood, personality, or behavior
  • clumsiness
  • change in walking or talking
  • decreased strength or weakness on one side of body
  • change in vision or speech

What side effects can this medicine cause?

Belatacept injection may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

  • headache
  • excessive tiredness
  • pale skin
  • fast heart beat
  • weakness
  • swelling of the hands, feet, ankles, or lower legs
  • constipation

Some side effects can be serious. If you experience any of these symptoms, or those listed in the IMPORTANT WARNING section, call your doctor immediately:

  • shortness of breath

Belatacept injection may cause other side effects. Call your doctor if you have any unusual problems while receiving this medication.

If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online ( ) or by phone (1-800-332-1088).

What other information should I know?

Keep all appointments with your doctor and the laboratory.

It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.

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