Tedizolid Injection

pronounced as (te diz' oh lid)

Brand Name(s): Sivextro®

Why is this medicine prescribed?

Tedizolid injection is used to treat skin infections caused by certain types of bacteria. Tedizolid is in a class of medications called oxazolidinone antibiotics. It works by stopping the growth of bacteria.

Antibiotics such as tedizolid injection will not work for colds, flu, and other viral infections. Using antibiotics when they are not needed increases your risk of getting an infection later that resists antibiotic treatment.

Are there other uses for this medicine?

This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.

How should this medicine be used?

Tedizolid injection comes as a solution to be given intravenously (into a vein) over 1 hour. It is usually given once or twice a day for 6 days.

You may receive tedizolid injection in a hospital or you may administer the medication at home. If you will be receiving tedizolid injection at home, your healthcare provider will show you how to use the medication. Be sure that you understand these directions, and ask your healthcare provider if you have any questions.

You should begin to feel better during the first few days of treatment with tedizolid injection. If your symptoms do not improve or get worse, tell your doctor.

What special precautions should I follow?

Before using tedizolid injection,

  • tell your doctor or pharmacist if you are allergic to this medication, any part of this medication, or any other medications, foods or substances. Tell your doctor or pharmacist about the allergy and what symptoms you had.
  • tell your doctor and pharmacist what other prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are using or taking or plan to take while using tedizolid injection Your doctor may need to change the doses of your medications or monitor you carefully for side effects.
  • tell your doctor if you have any medical conditions.
  • tell your doctor if you are pregnant, plan to become pregnant, or are breastfeeding. If you become pregnant while receiving tedizolid injection, call your doctor.
  • you should know that tedizolid injection may cause serotonin syndrome. If you experience any of the following symptoms, stop taking tedizolid injection and call your doctor immediately or go to the nearest hospital emergency room: fever, feeling hot, sweating more than usual, feeling restless or upset, trouble moving or balancing, stiff muscles or muscle twitching, unusual eye movement, or shaking.

What special dietary instructions should I follow?

Unless your doctor tells you otherwise, continue your normal diet.

What should I do if I forget to take a dose?

Use the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not use a double dose to make up for a missed one.

What should I do in case of overdose?

In case of overdose, call the poison control helpline at 1-800-222-1222. Information is also available online at https://www.poisonhelp.org/help . If the victim has collapsed, had a seizure, has trouble breathing, or can't be awakened, immediately call emergency services at 911.

What side effects can this medicine cause?

Tedizolid may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

  • nausea, vomiting, diarrhea
  • headache, dizziness
  • pain, redness, or swelling near the place where tedizolid was injected

Some side effects can be serious. If you experience any of these symptoms, call your doctor immediately:

  • severe diarrhea (watery or bloody stools) that may occur with or without fever and stomach cramps (may occur up to 2 months or more after your treatment)
  • numbness, tingling, burning, or pain sensation in your hands or feet
  • change or loss of vision

Tedizolid may cause other side effects. Call your doctor if you have any unusual problems while using this medication.

If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online ( https://www.fda.gov/Safety/MedWatch ) or by phone ( 1-800-332-1088).

What should I know about storage and disposal of this medication?

Your healthcare provider will tell you how to store your medication. Store your medication only as directed. Make sure you understand how to store your medication properly.

Keep all medication out of sight and reach of children as many containers are not child-resistant. Always lock safety caps. Place the medication in a safe location – one that is up and away and out of their sight and reach https://www.upandaway.org

Dispose of unneeded medications in a way so that pets, children, and other people cannot take them. Do not flush this medication down the toilet. Use a medicine take-back program. Talk to your pharmacist about take-back programs in your community. Visit the FDA's Safe Disposal of Medicines website https://www.fda.gov/drugs/safe-disposal-medicines/disposal-unused-medicines-what-you-should-know for more information

What other information should I know?

Keep all appointments with your doctor and the laboratory.

Do not let anyone else take your medication. Your prescription is probably not refillable. If you still have symptoms of infection after you finish the tedizolid, call your doctor.

Keep a written list of all of the prescription and nonprescription (over-the-counter) medicines, vitamins, minerals, and dietary supplements you are taking. Bring this list with you each time you visit a doctor or if you are admitted to the hospital. You should carry the list with you in case of emergencies.

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