Why is this medicine prescribed?
Linezolid injection is used to treat infections caused by bacteria. Linezolid is in a class of antibacterials called oxazolidinones. It works by stopping the growth of bacteria.
Antibiotics such as linezolid injection will not kill viruses that can cause colds, flu, or other infections. Using antibiotics when they are not needed increases your risk of getting an infection later that resists antibiotic treatment.
Are there other uses for this medicine?
This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.
How should this medicine be used?
Linezolid injection comes as a solution (liquid) to be infused into a vein. It is given as an intravenous infusion over 30 minutes to two hours, two to three times a day. Your doctor will determine how long you will receive linezolid injection.
Use linezolid injection exactly as directed. Do not use more or less of it or use it more often than prescribed by your doctor.
You may receive linezolid infusion in a hospital or doctor's office, or you may administer the medication at home. If you will be receiving linezolid infusion at home, your healthcare provider will show you how to use the medication. Be sure that you understand these directions, and ask your healthcare provider if you have any questions.
Continue to use linezolid injection until you finish the prescription, even if you feel better. Do not skip doses or stop using linezolid injection without talking to your doctor. If you stop using linezolid injection too soon or if you skip doses, your infection may not be completely treated and the bacteria may become resistant to antibiotics.
What special precautions should I follow?
Before using linezolid injection,
- tell your doctor or pharmacist if you are allergic to this medication, any part of this medication, or any other medications, foods or substances. Tell your doctor or pharmacist about the allergy and what symptoms you had.
- some medications should not be taken with linezolid injection. Other medications may cause dosing changes or extra monitoring when taken with linezolid injection. Make sure you have discussed any medications you are currently taking or plan to take before using linezolid injection with your doctor and pharmacist. Before starting, stopping, or changing any medications while using linezolid injection, please get the advice of your doctor or pharmacist.
- you should know that the following nonprescription products may interact with linezolid injection: pseudoephedrine and phenylpropanolamine. Be sure to let your doctor and pharmacist know that you are taking these medications before you start using linezolid injection. Do not start any of these medications while using linezolid injection without discussing with your healthcare provider.
- tell your doctor or pharmacist if you are taking following medications or have stopped taking them within the past two weeks: isocarboxazid, moclobemaide, phenelzine, rasagiline, selegiline, and tranylcypromine.
- tell your doctor if you have a chronic (long-lasting) infection, or if you have or have ever had diabetes, carcinoid syndrome (a condition where a tumor makes and releases too much serotonin), high blood pressure, hyperthyroidism (an overactive thyroid), immune suppression (problems with your immune system), pheochromocytoma (a tumor of the adrenal gland), seizures, or kidney disease.
- tell your doctor if you are pregnant, plan to become pregnant, or are breastfeeding. If you become pregnant while using linezolid injection, call your doctor.
- you should know that linezolid injection may cause serotonin syndrome. If you experience any of the following symptoms, stop taking tedizolid injection and call your doctor immediately or go to the nearest hospital emergency room: fever, feeling hot, sweating more than usual, feeling restless or upset, trouble moving or balancing, stiff muscles or muscle twitching, unusual eye movement, or shaking.
- if you are having surgery, including dental surgery, tell the doctor or dentist that you are using linezolid injection.
What special dietary instructions should I follow?
Avoid eating or drinking large amounts of foods and beverages containing tyramine while using linezolid injection. Foods and beverages that have been pickled, smoked, or fermented usually contain tyramine. These foods and beverages include alcoholic beverages, especially beer, Chianti, and other red wines; alcohol-free beer; cheeses (especially strong, aged, or processed varieties); sauerkraut; yogurt; raisins; bananas; sour cream; pickled herring; liver (especially chicken liver); dried meats and sausage (including hard salami and pepperoni); canned figs; avocados; soy sauce; turkey; yeast extracts; papaya products (including certain meat tenderizers); fava beans; and broad bean pods.
What should I do if I forget to take a dose?
Infuse the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not infuse a double dose to make up for a missed one.
What should I do in case of overdose?
In case of overdose, call the poison control helpline at 1-800-222-1222. Information is also available online at https://www.poisonhelp.org/help . If the victim has collapsed, had a seizure, has trouble breathing, or can't be awakened, immediately call emergency services at 911.
What side effects can this medicine cause?
Linezolid injection may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:
- headache
- nausea, vomiting, diarrhea; stomach pain
- change in the ways things taste
- rash, itching
- dizziness
- white patches in the mouth
- irritation, burning, or itching of the vagina
- change in color of the tongue or teeth
Some side effects can be serious. If you experience any of these symptoms, call your doctor immediately or get emergency medical treatment:
- hives, rash, itching, difficulty breathing or swallowing, swelling of the face, throat, tongue, lips, eyes, hands, feet, ankles, or lower legs, hoarseness
- blistering or peeling skin
- repeated nausea and vomiting; fast breathing; confusion; feeling tired
- pain, numbness, or weakness in hands, feet, or other parts of the body
- severe diarrhea (watery or bloody stools) that may occur with or without fever and stomach cramps (may occur up to 2 months or more after your treatment)
- unusual bleeding or bruising
- changes in color vision, blurred vision, or other changes in vision
- seizures
- muscle pain or tenderness; muscle weakness; dark or cola-colored urine
Linezolid injection may cause other side effects. Call your doctor if you have any unusual problems while using this medication.
If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online ( https://www.fda.gov/Safety/MedWatch ) or by phone ( 1-800-332-1088).What should I know about storage and disposal of this medication?
Your healthcare provider will tell you how to store your medication. Store your medication only as directed. Make sure you understand how to store your medication properly.
Keep all medication out of sight and reach of children as many containers are not child-resistant. Always lock safety caps. Place the medication in a safe location – one that is up and away and out of their sight and reach. https://www.upandaway.org Dispose of unneeded medications in a way so that pets, children, and other people cannot take them. Do not flush this medication down the toilet. Use a medicine take-back program. Talk to your pharmacist about take-back programs in your community. Visit the FDA's Safe Disposal of Medicines website https://goo.gl/c4Rm4p for more information.What other information should I know?
Keep all appointments with your doctor and the laboratory. Your doctor may order certain blood tests to check your body's response to linezolid injection.
Do not let anyone else use your medication. Your prescription is probably not refillable. If you still have symptoms of infection after you finish treatment with linezolid injection, call your doctor.
Keep a written list of all of the prescription and nonprescription (over-the-counter) medicines, vitamins, minerals, and dietary supplements you are taking. Bring this list with you each time you visit a doctor or if you are admitted to the hospital. You should carry the list with you in case of emergencies.